一、基本情况

李凌绪，男，1979年生，山东莱芜人。博士，副教授，入选青岛农业大学第四届1361人才工程第三层次，青岛农业大学农学与植保学院第三届师德标兵。研究方向为杂草抗药性、生物农药与仿生农药。先后主持或参加国家级及省部级科研项目10项，在国内外公开发表科研论文30篇，其中SCI论文11篇，获中华农业科技奖三等奖1项、青岛农业大学第一届青年教师讲课比赛三等奖1项。

二、 学习工作经历

2017.06- 菠菜广告联盟，副教授

2014.09-2017.06 青岛农业大学农学与植物保护学院，副教授

2008.08-2014.08 青岛农业大学化学与药学院，讲师

2006.11-2008.07 青岛农业大学植物保护学院，讲师

2004.09-2006.10 莱阳农学院植物保护系，助教

2011.09-2014.07 山东农业大学植物保护学院农药学专业，博士

2001.09-2004.07 福建农林大学植物保护学院农药学专业，硕士

1997.09-2001.07 山东农业大学植物保护学院植物保护专业，本科

三、 教学工作

主要担任植物保护专业植物化学保护、植物化学保护实验、农药加工技术等本科课程及杂草学研究方法等研究生课程的教学工作。主持校级教研项目1项、校多媒体网络课程1门，获山东省教学成果奖一等奖一项、青岛农业大学教学成果奖一等奖、三等奖各一项，获青岛农业大学第一届青年教师讲课比赛三等奖1项，获山东省优秀学士学位论文指导教师1项。

四、 研究方向及简介

主要从事杂草防治及抗药性机理研究，深入研究了我国稻茬麦田菵草对精噁唑禾草灵/甲基二磺隆的抗性机理，发现我国江苏、安徽、山东等省部分地区稻茬麦田菵草已对精噁唑禾草灵产生了高水平抗性，解析了其靶标抗性机理及非靶标抗性机理。

五、 科研课题

1. 菵草（Beckmannia syzigachne）对精噁唑禾草灵和甲基二磺隆多抗性的分子机制（31301680），24万，1/6，国家自然科学基金。

2. 抗性菵草代谢甲基二磺隆相关P450基因克隆与功能分析（ZR2019MC043），20万，1/6，山东省自然科学基金。

3. 基于菵草ACCase等位基因突变的适合度代价研究（3141787）80万，2/6，国家自然科学基金。

4. 具色素抑制作用的酰胺基香豆素的合成、构-效关系及作用机理研究（31471808）85万，3/9，国家自然科学基金。

六、主要成果

l 获奖

植物源仿生农用杀菌剂仿生安的研制与应用，2006－2007年度中华农业科技奖三等奖，9/10.

l 论文

[1] Shuang Bai, Yanfang Zhao, Yuanming Zhou, Mingliang Wang, Yihui Li, Xiaoyong Luo, Lingxu Li. Identification and expression of main genes involved in non‐target site resistance mechanisms to fenoxaprop‐p‐ethyl in Beckmannia syzigachne[J]. Pest Management Science, 2020, doi/abs/10.1002/ps.5800. IF=3.255

[2] Bingqi Liu, Fei Ding, Mingliang Wang, Fei Wang, Xiaoyong Luo, Lingxu Li*. Cross-resistance pattern to ACCase-inhibiting herbicides in a novel Trp1999Leu mutation American sloughgrass (Beckmannia syzigachne) population[J]. Pesticide Biochemistry and Physiology, 2019, 159:80-84. IF=2.87

[3] Mingliang Wang, Bingqi Liu, Yihui Li, Xiaoyong Luo, Lingxu Li*. Non–target site based resistance to the ALS-inhibiting herbicide mesosulfuron-methyl in American sloughgrass (Beckmannia syzigachne)[J]. Weed Science, 2019, 67: 527-533. IF=2.0

[4] Fei Ding^#, Lingxu Li^#, Wei Peng, Yukui Peng, Bingqi Liu. Molecular Basis for the Resistance of American Sloughgrass to Aryloxyphenoxypropionic Acid Pesticides and Its Environmental Relevance: A Combined Experimental and Computational Study [J]. Chemosphere, 2019, 235: 1030-1040. IF=5.108

[5] Lingxu Li, Xiaoyong Luo, Jinxin Wang. Resistance level and target-site mechanism to fenoxaprop-p-ethyl in Beckmannia syzigachne (Steud.) Fernald populations from China. Chilean Journal of Agricultural Research, 2017, 77(2):150-154.IF=0.78

[6] Lingxu Li, Weitang Liu, Yucheng Chi, Wenlei Guo, Xiaoyong Luo, Jinxin Wang. Molecular mechanism of mesosulfuron-methyl resistance in multiple-resistant

American sloughgrass (Beckmannia syzigachne Steud.).Weed Science, 2015, 63, 781-787.  IF=1.993

[7] Lingxu Li, Long Du, Weitang Liu, Guohui Yuan, Jinxin Wang. Target-site mechanism of ACCase-inhibitors resistance in American sloughgrass (Beckmannia syzigachne Steud.) from China. Pesticide Biochemistry and Physiology 2014, 110 C, 57-62.  IF=2.338

[8] Lingxu Li, Yaling Bi, Weitang Liu, Guohui Yuan, Jinxin Wang. Molecular basis for resistance to fenoxaprop-p-ethyl in American sloughgrass (Beckmannia syzigachne Steud.). Pesticide Biochemistry and Physiology, 2013,105(2):118-121.  IF=2.009

[9] 颜欣茹, 杨俊雪, 薛君, 刘嘉慧, 李凌绪^*. 抗性和敏感生物型菵草代谢精噁唑禾草灵的速度差异[J]. 杂草学报, 2017, 35(1): 15-19.

[10] 张相飞,李凌绪^*.正交试验法优化陈皮中橘皮素和川陈皮素的提取工艺. 湖北农业科学, 2015, 54 (21): 5364-5367.

[11] 张相飞, 杜春华, 郝双红, 李凌绪^*. 陈皮石油醚相中抗苹果腐烂病菌活性物质研究. 湖北农业科学, 2015, 54 (13): 3150-3153.

l 专利

含氟邻烯丙基苯酚类化合物的制备方法及农用生物活性(公开号CN102603493B), 杜春华, 许艳秋, 李凌绪.

l 专著

l 荣誉

八、联系方式

通讯地址：山东省青岛市城阳区长城路700号，菠菜广告联盟

邮政编码：266109

联系电话：13455276690

E-mail:lingxulipvi@126.com

1.Basic Situation

Lingxu Li, male, born in 1979, Shandong Laiwu people. Doctoral, associate professor, selected Qingdao Agricultural University fourth 1361 talent project third level, Qingdao Agricultural University College of agriculture and plant protection third teacher morality. Research direction for weed resistance, biological pesticides and bionic pesticides. Has hosted or participated in national and provincial and ministerial level scientific research project 10, published in domestic and foreign research papers 30, of which SCI papers 11, by the China Agricultural Science and Technology Award three prize 1, Qingdao Agricultural University, the first young teachers Lecture competition third prize 1 item.

2.Learning Work Experience

2017.06-So far College of Plant Medicine, Qingdao Agricultural University，Associate Professor

2014.09-2017.06 College of Plant Medicine, Qingdao Agricultural University，Associate Professor

2008.08-2014.08 College of Chemistry and Pharmacy, Qingdao Agricultural University，Lecturer

2006.11-2008.07 College of Plant Medicine, Qingdao Agricultural University，Lecturer

2004.09-2006.10 Department of Plant Protection, Laiyang Agricultural College，Assistant

2011.09-2014.07 College of Plant Protection, Shandong Agricultural University，Ph.D.

2001.09-2004.07 Fujian Agriculture and Forestry University, College of Plant Protection, Pharmacy,master's degree

1997.09-2001.07 Shandong Agricultural University College of Plant Protection, Plant Protection,Undergraduate

3.Teaching Work

Mainly served as plant protection professional phytochemical protection, pesticide processing technology courses such as teaching work. Presided over the school level teaching and research project 1, the school multimedia network course one, by the Qingdao Agricultural University, the first young teachers lecture third prize one

4.Research Direction And Profile

Mainly engaged in weed resistance research, in-depth study of China's wheat straw in the wheat straw on the anti-oxazole grass grass resistance mechanism, found that China's Jiangsu, Anhui, Shandong and other provinces in some areas of wheat straw Grasses have produced high levels of resistance. The resistance mechanism of the herbaceous plants was different from that of the resistant populations. I1781L, W2027C, I2041N, D2078G, G2096A and so on were identified from the resistant populations. Resistance mutation, and found that grass can be quickly metabolized by oxytetracyclovine to its resistance.

5.Research Subject

1.) Molecular mechanism of Beckmannia syzigachne resistance to fenoxazol and methyldimuron-methyl (31301680), 240,000, 1/6, National Natural Science Foundation of China.

2.)Study on the Secondary Metabolites of Orange Peanut with Active Antimicrobial Activity (ZR2010CQ026), 50,000, 1/7, Natural Science Foundation of Shandong Province.

3.) Based on the suitability of ACCase allele mutation (3141787) 800,000, 2/6, National Natural Science Foundation of China.

4.) Synthesis, structure-effect relationship and mechanism of amide-based coumarin with dye inhibition (31471808) 850,000, 3/9, National Natural Science Foundation of China.

5.)The ecological effects of imidacloprid on soil microbes and soil enzymes in cotton fields in the Yellow River Delta (41101488), 26 million, 3/6, National Natural Science Foundation of China.

6.) Development of new agricultural fungicides containing fluorine-containing o-hydroxyphenylbutanone (BS2009NY006), 60,000, 2/5, Science and Technology Department of Shandong Province.

7.)Research and development of new agricultural fungicides containing fluorine o-allyl phenols (J11LC21), 4.5 million, 2/7, Shandong Provincial Department of Education.

8.)The biological characteristics of the endophytic fungi J46 with herbicidal activity and the identification of its active components were identified, 50,000, 4/8, Natural Science Foundation of Shandong Province.

9.) With the agricultural bactericidal activity of psoralen bionic synthesis and development and application, 12 million, 7/7, Shandong Provincial Department of Education.

10.) Development of natural bactericidal substance 8-methyl-benzopyran-2-one, 40,000, 3/6, Qingdao Science and Technology Bureau.

6.Main Result

l Won The Award

Development and Application of Biomimetic Agricultural Biocide Biomimetic Biomass, 2006 - 2007 China Agricultural Science and Technology Award Third Prize, 9/10.

l Thesis

[1] Resistance level and target-site mechanism to fenoxaprop-p-ethyl in Beckmannia syzigachne (Steud.) Fernald populations from China. Journal of Chilean Agricultural Research, 2017, 77（2）Accepted.

[2] Lingxu Li, Weitang Liu, Yucheng Chi, Wenlei Guo, Xiaoyong Luo, Jinxin Wang. Molecular mechanism of mesosulfuron-methyl resistance in multiple-resistant

American sloughgrass (Beckmannia syzigachne Steud.).Weed Science, 2015, 63, 781-787. IF = 1.870

[3] Lingxu Li, Long Du, Weitang Liu, Guohui Yuan, Jinxin Wang. Target-site mechanism of ACCase-inhibitors resistance in American sloughgrass (Beckmannia syzigachne Steud.) from China. Pesticide Biochemistry and Physiology 2014, 110 C, 57-62. IF = 2.009

[4] Lingxu Li, Yaling Bi, Weitang Liu, Guohui Yuan, Jinxin Wang. Molecular basis for resistance to fenoxaprop-p-ethyl in American sloughgrass (Beckmannia syzigachne Steud.). Pesticide Biochemistry and Physiology, 2013,105(2):118-121.IF = 2.111

[5] 张相飞,李凌绪*.正交试验法优化陈皮中橘皮素和川陈皮素的提取工艺. 湖北农业科学, 2015, 54 (21): 5364-5367.

[6] 张相飞, 杜春华, 郝双红, 李凌绪*. 陈皮石油醚相中抗苹果腐烂病菌活性物质研究. 湖北农业科学, 2015, 54 (13): 3150-3153.

[7] 李凌绪, 张相飞, 程艳静. 电导率法筛选陈皮油微乳, 中草药, 2012, 43 (12): 2396-2400.

[8] 李凌绪, 陈彦翠, 郝双红. O/W微乳对肉桂油的增溶作用. 时珍国医国药, 2012, 23 (1): 17-18.

[9] 李凌绪, 杜春华.牡荆油自乳化释药系统的制备. 青岛农业大学学报(自然科学版), 2011, 28 (4): 209-312.

[10] 李凌绪, 曲亮亮, 孟昭礼. 橘皮色素抑菌活性研究. 湖北农业科学, 2010, 49 (1): 80-82.

[11] 李凌绪, 魏艳, 杜春华, 孟昭礼, 王永良. 桔皮提取物对七种农业植物病原真菌活性初探. 安徽农业科学, 2008,36 (30): 13242-13243.

l Patent

Preparation method of fluorine-containing o-allylphenols and agricultural bioactivities (Publication No. CN102603493B), Chunhua Du, Yanqiu Xu, Lingxu Li.Monographs

l Honor

8. contact information

Address: No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province, Qingdao Agricultural University, College of Plant Medicine

Post code: 266109

Tel:13455276690

E-mail:lingxulipvi@126.com